Sulfonated-Titanomagnetite Nanoparticles as Potential and Recyclable Catalyst for the Synthesis of Dihydroquinazoline and Hexahydroquinoline Derivatives under Solvent-Free Condition

Document Type : Research Article

Authors

1 Department of Chemistry, Bu-Ali Sina University, Hamedan, I.R. IRAN

2 Nano Drug Delivery Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, I.R. IRAN

Abstract

The performance of sulfonated-titanomagnetite nanoparticles (Fe3-xTixO4-SO3H NPs)as useful and recyclable nanocatalyst for the synthesis of dihydroquinazoline and hexahydroquinoline derivatives through multi-component reaction approach in solvent-free condition were investigated extensively. The successful synthesis of mentioned derivatives was confirmed using Fourier-Transform InfraRed (FT-IR) as well as 1H/13C nuclear magnetic resonance (NMR) spectroscopies. According to the results, the employed nanocatalyst has some advantages such as high catalytic activity in short reaction time, good-to-excellent isolated yields in most cases, easy workup process, smooth processing feature of the reactions, facile recovery using an external magnetic field,  and re-usability for four times without significant loss in its activity.

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References

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Iranian Journal of Chemistry and Chemical Engineering
Volume 40, Issue 2 - Serial Number 106
March and April 2021
Pages 367-381

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